Biochemistry


Vedolizumab free anti-drug antibodies

Specimen

Serum

Special instructions

Trough (pre dose) specimen required

Units

AU/mL (Arbitrary Units per mL)

Test Usage

Immunogenicity to biologic drugs such as vedolizumab is a possible cause of treatment failure. The assay used to measure antibodies to Vedolizumab is drug-sensitive and can only detect ‘free’ antibodies that are unbound to drug, meaning that antibodies are unlikely to be detected in the presence of Vedolizumab drug. On this basis we will only perform anti-drug antibody analysis after the drug level has been analysed and is found to be <3.1 mg/L.

Specimen Labelling Procedure