Welcome to the Exeter Clinical Laboratory International website
NHS logo

Anti-Streptococcal Serology



The Virology Department at RDE has ceased all Anti-DNase B testing (as of 17th November 2023.)  We will continue to test for Anti-streptolysin O antibodies.

BioMérieux are stopping the commercialisation of the ASD ANTIBODY TESTING KIT, and there is no alternative on the market within Europe. We have received a notification stating the below;

BioMérieux has made every effort to maintain this product on the market for a long time. Following the evolution of the European regulations, and on-going difficulties in the manufacture of this product we regret to inform you that we have taken the difficult decision to end its commercialization by the 31st March 2023.‘

We are sorry for any difficulties this may cause. If there are any queries or comments relating to these changes please contact the laboratory by email at rduh.microconsultants@nhs.net.

Test Usage

The ASO (Anti-Streptolysin O) test is used to diagnose recent streptococcal infection in post-streptococcal conditions, such as glomerulonephritis and rheumatic fever.


Blood sample (serum)

Specimen container

Gold top clotted (min 4ml)

How To Request On EPIC

For electronic requesting using EPIC (RDUH ONLY):

Search for: ‘Antistreptolysin O (ASO) Serology‘ or test code ‘LAB1178

Special Instructions

Please include full clinical details, including onset date (antibodies appear 1 week to 1 month after infection).


Processed locally in Microbiology at RDUH

Turnaround Time

2 – 16 days (batched and run on alternate weeks)

Useful Links

For Healthcare professionals:

Antistreptolysin O titre – GPnotebook

(Key words: ASO, ASOT, antistreptolysin)

Specimen Labelling Procedure
University of Exeter logo
UKAS Medical logo


Royal Devon University Healthcare logo