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Antibiotic Assays

 

Processed in Blood Sciences lab – send sample to Blood Sciences – expect result within 24 hours:

Antibiotic Pre Dose Post Dose Comments  Performing Lab Epic Test Code
Gentamicin (once daily) Not required 6-14 hours Urban & Craig nomogram Blood Sciences, RDUH LAB27
Tobramycin Not required 6-14 hours Blood Sciences, RDUH LAB37
Gentamicin (Endocarditis dosing) 48 hours 1-2 hours See MicroGuide Blood Sciences, RDUH LAB27
Vancomycin 48 hours Not required See MicroGuide Blood Sciences, RDUH LAB40

 

These are sent to Bristol automatically – expect result within 48 hours:

Antibiotic Pre Dose Post Dose Comments  Performing Lab Epic Test Code
Amikacin 48 hours 1-2 hours Southmead Hospital LAB145
Netilmicin 48 hours 1-2 hours Southmead Hospital LAB9286
Itraconazole 7 days Not required Southmead Hospital LAB9282
Voriconazole 5 days Not required Southmead Hospital LAB9294
Posaconazole (suspension only) 5 days Not required Southmead Hospital LAB9287
Teicoplanin 48 hours Not required Southmead Hospital LAB9292

 

These will only be undertaken after discussion/agreement from Microbiology – Generally take pre-dose levels AFTER drug will have reached steady state (7 days):

Antibiotic Pre Dose Post Dose Comments  Performing Lab Epic Test Code
Acyclovir 7 days 1-2 hours Southmead Hospital LAB9266
Ciprofloxacin 7 days 1-2 hours Southmead Hospital LAB9270
Colistin 7 days Not required Southmead Hospital LAB9272
Cycloserine 7 days 3-4 hours Southmead Hospital LAB9274
Daptomycin 7 days 1-2 hours Southmead Hospital LAB9275
Ethambutol 7 days 2 hours EDTA blood Cardiff Toxicology lab LAB9276
Flucloxacillin 7 days 1-2 hours Southmead Hospital LAB9277
Flucytosine 7 days 1-2 hours Southmead Hospital LAB9278
Ganciclovir 7 days 1-2 hours Southmead Hospital LAB9279
Isoniazid 7 days 2 hours EDTA blood Cardiff Toxicology lab LAB9281
Linezolid 7 days 1-2 hours Southmead Hospital LAB9284
Penicillin 7 days 1-2 hours Send on ice Southmead Hospital LAB9397
Rifampicin (oral) 7 days 1, 2 & 4 hours Southmead Hospital LAB9288
Rifampicin (oral)   2 hours EDTA blood Cardiff Toxicology lab LAB9288
Streptomycin 48 hours 1-2 hours Southmead Hospital LAB9290
Sulphamethoxazole (In Co-trimoxazole) 7 days 1-2 hours Southmead Hospital LAB9398
Trimethoprim (In Co-trimoxazole) 7 days 1-2 hours Southmead Hospital LAB9399

 

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