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Aspergillosis is the name for a group of conditions caused by Aspergillus mould.



Isolation of Aspergillus for identification and sensitivities (if required.)

Aspergillus Antibody (precipitins)

Detection of antibodies to Aspergillus spp. Appropriate for the diagnosis of aspergillosis in immunocompetent patients e.g. allergic bronchopulmonary aspergillosis (ABPA), aspergilloma, chronic necrotising aspergillosis, aspergillus sinusitis

 Aspergillus antigen

This test detects the presence of the Aspergillus antigen galactomannan in serum or BAL fluid to diagnosis invasive aspergillosis in immunocompromised patients.

Aspergillus PCR

Detects presence of Aspergillus DNA in whole blood or BAL fluid. Generally used serially to detect rising levels post-bone marrow transplant.


Culture: Nose Swab, Tissue biopsy, Broncho-alveolar lavage (BAL), Sputum, Blood Cultures

Serology: Blood

PCR: Blood, BAL

Specimen container

  • Nose swab –  Transwab
  • Biopsy –  Plain Universal Sterile Universal Pot
  • BAL –  Plain Universal Sterile Universal Pot
  • Sputum – Sputum Pot
  • Blood culture – Blood Culture Bottles
  • Blood – Serology (Gold top tube, SST), PCR (Pink top tube, EDTA)

How To Request On EPIC

For electronic requesting using EPIC (RDUH ONLY):

For respiratory sample culture search for: ‘Respiratory Sample MC&S‘ or test code ‘LAB900‘ and include relevant clinical details such as ABPA or state ‘Fungal culture required’

For blood cultures see: Blood Cultures

For serology search for: ‘Fungal Serology‘ or test code’LAB9315

For PCR search for: ‘Aspergillus PCR‘ or test code ‘LAB9264

Special Instructions

Usually only relevant in immunocompromised patients.


Culture – Processed locally in Microbiology at RDUH

PCR/ Serology – Sent to UKHSA Mycology Reference Laboratory, UKHSA South West, Bristol

Processing Time

Culture – up to 2 weeks

Serology/ PCR – up to 1 week

Urgent Specimen Instructions

D/W Consultant Microbiologist

Useful Links

For Patients:

Aspergillosis – NHS

Fungal Infections – Lab Tests Online UK

Aspergillosis | Asthma + Lung UK

For Healthcare Professionals:

Aspergillosis – Symptoms, diagnosis and treatment | BMJ Best Practice

Allergic bronchopulmonary aspergillosis – Symptoms, diagnosis and treatment | BMJ Best Practice

Mycology reference laboratory

Specimen Labelling Procedure Procedure for Collection of Blood Cultures
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