Aspergillosis is the name for a group of conditions caused by Aspergillus mould.
Isolation of Aspergillus for identification and sensitivities (if required.)
Detection of antibodies to Aspergillus spp. Appropriate for the diagnosis of aspergillosis in immunocompetent patients e.g. allergic bronchopulmonary aspergillosis, aspergilloma, chronic necrotising aspergillosis, aspergillus sinusitis
This test detects the presence of the Aspergillus antigen galactomannan in serum or BAL fluid to diagnosis invasive aspergillosis in immunocompromised patients.
Detects presence of Aspergillus DNA in whole blood or BAL fluid. Generally used serially to detect rising levels post-bone marrow transplant.
Culture: Nose Swab, Tissue biopsy, Broncho-alveolar lavage (BAL), Blood Cultures
Usually only relevant in immunocompromised patients.
Culture – processed in-house at RD&E
PCR/ Serology – sent to Reference Laboratory
Aspergillus Ag / Precipitins /PCR – Bristol UKHSA Laboratory
Culture – up to 2 weeks
Serology/ PCR – up to 1 weeks
D/W Consultant Microbiologist