CMV Saliva PCR

Microbiology

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PLEASE NOTE: This Test/procedure is not currently included in the defined scope of the laboratory’s UKAS Accreditation, (ISO15189) schedule.

This test has passed internal laboratory verification and been reviewed clinically prior to being brought into use.

Summary

Nucleic acid amplification assay for the detection of Cytomegalovirus (CMV) DNA extracted from neonatal saliva swabs.

The assay used detects a specific target in the exon 4 region of the CMV MIEA gene (major immediate early antigen.)

Usage

Diagnosis of congenital CMV infection in new-borns.

Background

CMV is a double stranded DNA virus of the Herpesvirus family. Congenital CMV infection is the leading infectious disease cause of hearing loss in babies.

Specimen

Buccal/saliva swab in viral transport media

Specimen Container

Copan or Virocult swab

High Risk Specimens

Requests must indicate if a specimen is high risk. Please indicate details of the risk e.g. TB, MPox, Viral Haemorrhagic Fever.

For more details please see our guidance on high risk specimens.

Urgent Specimen Instructions

Please contact the laboratory to discuss any urgent requests.

Availability

Processed locally in Microbiology at RDUH

Turnaround Time

5 days

Reporting

CMV will be reported as follows:

CMV Not detected
CMV Detected at low level
CMV Detected

Method

ELITech ELITe InGenius

Useful Links

For Patients

Cytomegalovirus (CMV) – Lab Tests Online UK

Cytomegalovirus (CMV) – NHS

For Healthcare Professionals

Cytomegalovirus – Patient.info

 

Specimen Labelling Procedure