Blood sample (serum)
Gold top clotted (5ml)
Please give details of following clinical symptoms:
Acute Hep A is mostly (75%) asymptomatic. In cases of acute hepatitis, also request Hepatitis B, Hepatitis C and Hepatitis E.
Please request HAV IgG for immunity screen.
HAV IgM is used for diagnosis of acute infection. Please discuss with the Consultant Microbiologist before sending this test – we need to know risk factors, and details of high risk secondary contacts who might need HNIG prophylaxis (over 50, chronic liver disease, or immunosuppression). This test has a relatively low positive predictive value due to non-specific reactogenicity so it is important to pre-select those tested.