Blood Sciences Test

Anti-Nuclear Antibodies (ANA / ANF)



Special Instructions

Minimum sample volume: 3 ml

Factors affecting results

None known

Reference Ranges

Not applicable

Test Usage

Antinuclear antibodies are present at high titre in SLE and other connective tissue diseases, and at lower titre in rheumatoid arthritis, other autoimmune diseases and in 10% of normal elderly. A homogenous pattern is associated with dsDNA antibodies, while a speckled pattern is associated with antibodies to extractable nuclear antigens (ENA). The laboratory will automatically perform dsDNA and ENA antibodies where appropriate.

Turnaround time

7 days


In House

Clinical Advice

Clinical advice is available from the Immunology Medical Team at Derriford Hospital

T: 01752 431675


Specimen Labelling Procedure