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BETA2/β2 Glycoprotein 1 antibodies

Blood Sciences Test


Test Usage

β2-Glycoprotein I is intended for the in vitro quantitative measurement of IgG and IgM antibodies directed to β2-Glycoprotein I in human serum to aid in the diagnosis of antiphospholipid syndrome (APS) and to evaluate the thrombotic risk in patients with systemic lupus erythematosus (SLE).

Positive B2GP1 are not diagnostic and clinical correlation is essential. Lupus anticoagulant should be checked and B2GP1 antibodies should be repeated at least 12 weeks apart to provide evidence of a persistent autoantibody present.

Reference Range

  • Negative: 10.0 U/mL
  • Positive:    >10.0 U/mL

Specimen

Serum

Special Instructions

Minimum sample volume: 3 ml

Turnaround time

Weekly

Availability

In House

Clinical Advice

Clinical advice is available from the Immunology Medical Team at Derriford Hospital

T: 01752 431675

E: plh-tr.eden@nhs.net

Assayed By

Royal Devon & Exeter Hospital (Wonford)

Specimen Labelling Procedure
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A UKAS Accredited Medical Laboratory

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