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Blood Sciences Test


1 x Non-gel tube (6 mL) and 1 x large whole blood EDTA transfusion tube (6 mL).

Both tubes should be filled to 6mL.

Special Instructions

It is extremely important that a strict procedure is adhered to when collecting blood for cryoglobulins. Any variation from the procedure can lead to premature cryoprecipitation and a potential false negative result.

The laboratory must be contacted beforehand and a trained member of staff will attend the venepuncture. Pre-warmed collection tubes will be provided by the laboratory and handed to the phlebotomist once the syringe has been inserted into the patient’s arm. The sample will then be transported to the laboratory at 37°C. It may be more convenient for patients of General Practitioners to have the blood sample taken in the Medical Outpatients Blood Room at the Royal Devon and Exeter Hospital (Wonford) so that this procedure can be adhered to.

Factors affecting results

None known

Reference Ranges

Not applicable

Test Usage

For the detection of cryoglobulinaemias, on the direction of an Immunology Consultant.


The Immunology laboratory provides this test Monday to Thursday, 09:00-16:30.

Turnaround time

10 days

Clinical Advice

Clinical advice is available from the Immunology Medical Team at Derriford Hospital

T: 01752 431675

E: plh-tr.eden@nhs.net


Please note this test is not UKAS accredited

Specimen Labelling Procedure
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