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Muscle Specific Kinase (MuSK) Antibodies

Blood Sciences Test


Specimen

Serum

Special Instructions

Minimum sample volume: 3 ml

Test Usage

Muscle specific tyrosine kinase (MuSK) is a surface membrane enzyme that is essential in aggregating Acetylcholine receptor during the development of the neuromuscular junction. Recent studies have shown that antibodies to MuSK are present in 40% to 50% of patients with generalised Acetylcholine Receptor seronegative myasthenia gravis. Anti-MuSK antibodies have not been found in patients with purely ocular myasthenia or in those with anti-acetylcholine receptor antibodies.

Turnaround time

Monthly

Availability

Referred Test

Assayed By

This investigation is performed at the Immunology Department, Churchill Hospital, Headington, Oxford, OX3 7LJ

 

Specimen Labelling Procedure
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