Blood Sciences Test


NT-pro-BNP

Specimen

Serum

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Units

ng/L

Reference Range

M <45 Y 0 – 63 ng/L
M 45 – 55Y 0 – 84 ng/L
M 55- 65Y 0 – 161 ng/L
M 65 – 75 0 – 241 ng/L
M >75Y 0 – 486 ng/L

F <45Y 0 -116 ng/L
F 45 – 55Y 0 – 169 ng/L
F 55 – 65Y 0 -247 ng/L
F 65 – 75Y 0 – 285 ng/L
F >75Y 0 – 738 ng/L

NT-Pro-BNP is recommended for ruling-out Heart Failure, but not to establish the diagnosis.

A serum NT-Pro-BNP level <400 ng/L in an untreated patient makes a diagnosis of heart failure unlikely.  Refer patients with suspected heart failure to have transthoracic Doppler 2D echocardiography for NT Pro BNP level between  400-2000  ng/L within 6 weeks and refer within 2 weeks for level >2000 ng/L [NICE CG108 Chronic Heart Failure in Adults: Management].

NT-pro-BNP can be elevated in chronic kidney disease and in cardiac conditions other than heart failure e.g. aortic stenosis, AF, pulmonary embolism and uncontrolled hypertension.

Test Usage

The N-terminal Pro-Brain Natriuretic Peptide (NT-Pro-BNP) is an assay used as an aid in the diagnosis of individuals suspected of having congestive heart failure. The test is further indicated for the risk stratification of patients with acute coronary syndrome and congestive heart failure.

Turnaround Time

24 hours

Availability

Local test

Can be added on to an existing request up to 4 days following sample receipt

Minimum Repeat Interval

6 months

Specimen Labelling Procedure