SHBG is a serum globulin that binds testosterone and, to a lesser extent oestradiol. On its own, it has little diagnostic value but it is required when measuring the biologically active free testosterone fraction as distinct from the 98% of total testosterone which is bound and inactive.
SHBG is increased by: oestrogens, pregnancy, androgen deficiency, thyrotoxicosis, cirrhosis.
To calculate free testosterone, go to: http://www.issam.ch/freetesto.htm
***NEW CALIBRATION FROM 30TH OCTOBER 2019***
|SHBG concentration level (nmol/L)||Number Tested:||Mean bias (nmol/L):||Bias %|
Due to an equipment upgrade and assay re-calibration, the results reported for SHBG may be up to 18% lower than those reported before 30/10/19, with a proportional increase in calculated free androgen index. Clinical cut-offs have not changed.
Can be added on to an existing request up to 4 days following sample receiptSpecimen Labelling Procedure