Tissue Transglutaminase (TTG)

Blood Sciences Test

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Specimen

Serum

Special Instructions

Minimum sample volume: 3 ml

Reference Range

• Negative : ≤10.0 U/mL
• Positive:    >10.0 U/mL

Test Usage

IgA TTG antibodies have replaced IgA gliadin, IgG gliadin and IgA endomysial antibodies as the screening test for coeliac disease.

Positive results will be confirmed using IgA endomysial antibodies.

A negative TTG result makes a diagnosis of  Coeliac disease unlikely, unless IgA deficient or on gluten free diet.

Turnaround time

Weekly

Availability

In House

Clinical Advice

Clinical advice is available from the Immunology Medical Team at Derriford Hospital

T: 01752 431675

E: plh-tr.eden@nhs.net

Assayed By

Royal Devon & Exeter Hospital (Wonford)

Specimen Labelling Procedure