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Vedolizumab free anti-drug antibodies

Biochemistry Blood Sciences Test


**Please note; Change to requesting procedure **

As of the 27/12/21, Vedolizumab antibodies will be reflexed onto all undetectable drugs levels. With these changes in place, you will only need to request Vedolizumab drugs, Vedolizumab antibody levels will be added on as a reflex test when the drug level is undetectable.

**Please note; return to normal vedolizumab drug and antibody level service **

The manufacturing issue has now been resolved. We are pleased to say we have returned to normal service. We apologies for any inconvenience this delay may have caused.

Specimen

Serum

Special instructions

Trough (pre dose) specimen required

Units

AU/mL (Arbitrary Units per mL)

Test Price

£85.27*

NHS referral price

Test Usage

Immunogenicity to biologic drugs such as vedolizumab is a possible cause of treatment failure. The assay used to measure antibodies to Vedolizumab is drug-sensitive and can only detect ‘free’ antibodies that are unbound to drug, meaning that antibodies are unlikely to be detected in the presence of Vedolizumab drug. On this basis we will only perform anti-drug antibody analysis after the drug level has been analysed and is found to be <3.1 mg/L.

Referrals

We welcome referrals for Vedolizumab total Ab monitoring. If you are a new requestor please complete the following form: New requestor form. 

We now also have the option to use NPEx for referral requesting.

Further information about sample requirements for this test can be found here: Vedolizumab and Anti-Vedolizumab Antibodies – further information

Specimen Labelling Procedure

Specimen Labelling Procedure
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8210

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