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Antenatal Screen



Serology testing for:

Syphilis Antibodies

Hepatitis B Surface Antigen

HIV Antibodies/Antigen

Test Usage

Screening in first trimester of pregnancy


Blood sample (serum)

Specimen container

Gold top clotted (5ml)

How to request on EPIC

For electronic requesting using EPIC (RDUH ONLY):

Search for: ‘First Trimester Serology Screen‘ or test code ‘LAB701

Special Instructions

It should be clearly documented in the woman’s handheld notes which tests have been offered / discussed and that written information has been given

If any tests declined this should be clearly documented – otherwise the laboratory will perform all tests routinely.


Processed locally in Microbiology at RDUH

Turnaround Time

2 days (compliant with IDSPS guidelines)

Urgent Specimen Instructions

D/W Consultant Microbiologist if an unscreened woman presents late in pregnancy or in labour. Urgent out-of-hours testing is offered in high risk groups in order that appropriate treatment with prophylaxis can be offered to the infant.

Useful Links

For Patients:

Screening for hepatitis B, HIV and syphilis – NHS (www.nhs.uk)

Pregnancy | Lab Tests Online-UK

Pregnancy Screening Tests (Antenatal Checks) | Patient.info

For Healthcare professionals:

Infectious diseases in pregnancy screening (IDPS): programme overview – GOV.UK (www.gov.uk)

Specimen Labelling Procedure
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