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Hepatitis B Serology

Microbiology


Specimen

Blood sample (serum)

Specimen container

Gold top clotted 5ml

Special Instructions

Please give details of following clinical symptoms:

  • Acute Jaundice
  • Malaise
  • Abdominal pain
  • Nausea
  • ALT>400

Acute Hep B is mostly (70%) asymptomatic. In cases of acute hepatitis, also request Hepatitis A IgM, Hepatitis C and Hepatitis E.

Test Usage

Diagnosis of past / acute infection with Hepatitis B

Test selection:

  • Hepatitis B Surface antigen ( HBsAg)– use for diagnosis of acute ongoing infection/ carrier status
  • Hepatitis B Surface antibody ( HBsAb) – determination of immunity
  • Hepatitis B e markers – determination of infectivity in carrier status in HBsAg positive patients.
  • Hepatitis B Core Antibody – to determine past infection, and as a marker of potential occult infected. Tested pre-chemotherapy & monoclonal antibodies.

Availability

Local test

Processing Time

24- 48 hours

Urgent Specimen Instructions

Please phone the laboratory for advice urgent tests / needlestick injuries etc

Reference

https://www.gov.uk/government/collections/hepatitis-b-guidance-data-and-analysis

(Key words: HepB)

Specimen Labelling Procedure
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